Blar i forfatter "Varghese, George M."

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    • Secreted wnt antagonists in scrub typhus 

      Ueland, Thor; Astrup, Elisabeth; Otterdal, Kari; Lekva, Tove; Janardhanan, Jeshina; Prakash, John A.; Thomas, Kurien; Michelsen, Annika; Aukrust, Pål; Varghese, George M.; Damås, Jan Kristian (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-29)
      Background - The mechanisms that control local and systemic inflammation in scrub typhus have only been partially elucidated. The wingless (Wnt) signaling pathways are emerging as important regulators of inflammation and infection, but have not been investigated in scrub typhus. <p> <p>Methodology/Principal findings - Plasma levels of secreted Wnt antagonists (i.e. DKK-1, sFRP-3, WIF-1 and SOST) ...